How B.LAB’s Biome Serum Supports the DEJ — Not Just the Epidermis

Skin doesn’t just age on the surface. This serum targets where regeneration begins.

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Skincare That Works Beyond the Epidermis

Most serums target the epidermis—hydrating, plumping, or resurfacing the uppermost layers. But true ageing begins below: in the dermal-epidermal junction (DEJ), the structural interface where skin’s regeneration, strength, and signal traffic are coordinated.

B.LAB’s AgeBiome™ Biome Serum is engineered for this exact zone. Through targeted signal peptides and microbiome modulators, it helps retrain skin’s biological memory—restoring function, not just improving surface appearance.

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What Is the DEJ — And Why It Matters

The dermal-epidermal junction is a thin but critical layer that:

• Anchors the epidermis to the dermis

• Facilitates nutrient and cytokine exchange

• Coordinates cell renewal and collagen remodeling

• Deteriorates with age, stress, and inflammation

When the DEJ breaks down, skin loses structure, resilience, and the ability to regenerate efficiently. This leads to visible sagging, dullness, and slower healing.

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What the Biome Serum Does Differently

The AgeBiome™ Biome Serum is not just a hydration booster. Its formulation is designed to:

• Deliver bioactive peptides that signal DEJ fibroblasts

• Support post-exfoliation microflora recovery

• Restore pH balance and reduce low-level inflammation

• Recondition the DEJ to receive and respond to stimuli

It’s a retraining tool for tired skin—not just a topical smoother.

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Mechanism of Action

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This layered activity allows the skin to regain regenerative behavior, especially after exfoliation or dermal stress.

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Why Epidermal-Only Serums Aren’t Enough

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The Biome Serum is best used immediately post-exfoliation, when pathways are open and the DEJ is most receptive to signal cues.

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When & How to Use It

Use as part of the AgeBiome Reset Ritual or after any in-clinic skin clearing service. Best results come when paired with:

• Weekly exfoliation (acid or enzyme)

• Optional dermarolling (2–3x/week)

• Recovery layering (mask or lipid barrier finish)

Apply 2–4 drops on freshly cleansed or exfoliated skin, ideally in the evening.

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Who It’s For

• Skin showing age-related stagnation (dullness, uneven tone, poor bounce)

• Post-treatment recovery clients needing biome recalibration

• Users looking for results deeper than moisturization

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Key Takeaways

• The DEJ is the command center for skin regeneration and bounce

• AgeBiome™ Biome Serum is engineered to activate and retrain this zone

• It combines signal peptides + microbiome regulators + repair logic

• Works best after exfoliation, when signal reception is biologically primed

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Ask Your Therapist

Want to know if your DEJ is underperforming? Ask for a Skin Turnover Analysis or Biome Function Diagnostic at your next B.LAB appointment. This helps determine your optimal exfoliation and serum layering rhythm.

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